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Cohenmehr OptometryVision · Dry Eye · Keratoconus Center
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Medically reviewed by Dr. Bijan Cohenmehr, OD Last reviewed

Prescription Dry Eye Drops in Los Angeles

Medication matched to your pattern of dryness.

When artificial tears and home care aren’t enough, prescription medication treats the root causes of dry eye — inflammation, poor tear production, and fast evaporation. We rarely rely on just one: your plan is built to work alongside IPL, plugs, lid therapies or scleral lenses.

Prescription dry eye medications
Anti-inflammatory
Restasis®, Cequa®, Vevye®, Xiidra®
Tear-stimulating
Tyrvaya® spray, Tryptyr®
Evaporation
Miebo® and similar
Short-term
Steroid “boosts” (loteprednol)

The toolbox, by job

  • Cyclosporine drops (Restasis®, Cequa®, Vevye®) quiet inflammation so your own glands work better — gradually, over weeks to months
  • Xiidra® (lifitegrast) targets inflammation a different way; many notice less burning and wind sensitivity
  • Tyrvaya® nasal spray signals your body to produce more natural tears — useful when drops aren’t tolerated
  • Miebo® supports the oily layer so tears don’t vanish seconds after you blink
  • Tryptyr® (acoltremon), the first FDA-approved TRPM8 agonist, stimulates natural basal tear production
  • Short steroid courses reset angry, inflamed eyes so long-term therapy can work

Not instant — intentional

These medications change the environment of the eye surface rather than coating it. Consistency over weeks is what makes tears more stable and comfortable.

Your plan

Matched, monitored, adjusted.

Our optometrists in Los Angeles review your exam findings and dryness type, choose medications that fit your pattern, and help navigate insurance and prior authorizations. With newer drops like Tryptyr, we typically reassess in 2–4 weeks — tear volume, staining, symptoms — then fine-tune the broader plan.

Most prescription dry eye medications are medical treatments and are often covered by insurance, sometimes with prior authorization.

Beyond drops

Severe cases have further options.

  • Thicker nighttime gels and ointments for sleep
  • Combination regimens pairing medication with IPL, plugs, or scleral lenses
  • Autologous serum drops, in select cases, made from your own blood components
Book a dry eye evaluation

Common questions

Prescription drops, answered.

Anything else, call the office at 310-828-2010.

  • Anti-inflammatory drops build over weeks to months. Short steroid courses bridge the gap when eyes are flared.

  • Mild burning on starting cyclosporine is common and usually settles; preservative-free tears can help with comfort.

  • That depends on whether your problem is inflammation, low tear volume, fast evaporation — or a mix. The exam decides.

  • Restasis (cyclosporine 0.05%) is a prescription drop that increases the eye's own tear production when inflammation has suppressed it, as in chronic dry eye. It is used twice a day, about 12 hours apart. Burning when you first start it is the most common side effect; in the approval studies about 17% of patients reported it.

  • Weeks to months. Cyclosporine works by calming the inflammation that holds tear production down, and that takes time: the studies behind its approval measured the gain in tear production at six months. A short course of a steroid drop can bridge the first weeks when the eyes are flared.

Also consider

Next step

Get past the artificial-tears plateau.

Book an evaluation and leave with a medication plan matched to your dryness.

Book Today Or call 310-828-2010